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INDIANOLA, Iowa ? Republican presidential hopeful Rick Perry said Wednesday that he has "always struggled" with his position on abortion and clarified remarks he made a day earlier to indicate he would allow abortion if a woman's life were at risk.
The Texas governor, campaigning hard in the final week ahead of Iowa's lead-off Jan. 3 caucuses, had told a pastor Tuesday that he had undergone a "transformation" on abortion rights after meeting a woman, Rebecca Kissling, who said she was conceived during a rape. She was featured in former Arkansas Gov. Mike Huckabee's anti-abortion documentary, "The Gift of Life," and Perry attended its Iowa premier.
A day later, Perry said he opposes abortion rights in cases of rape and incest, but would allow the legal procedure if the pregnancy threatened the mother's life.
"I think I've always struggled with that issue," Perry told reporters after meeting with voters in a sports bar. "After I went to see the movie a `Gift of Life' and had a conversation with Rebecca Kissling, and I really thought about this through the Christmas holidays and that's the conclusion I came to."
Asked if a mother's life was the only instance when he would allow abortion, he was concise as he boarded his bus: "That's correct."
In his push before Iowa holds its first caucuses, Perry is playing up his social conservative credentials. But his late shift on abortion drew questions about what exactly he believed on the issue many Iowans make their top priority.
A Time-CNN poll released Wednesday showed only 19 percent of those likely to caucus view cultural issues such as abortion and gay rights were unimportant to their selection of a candidate. A separate New York Times-CBS News poll earlier this month said 32 percent of likely Republican caucus-goers said they would not support and candidate who changed positions on abortion.
In Osceola on Tuesday, Perry told a voter he had changed his view.
"You're seeing a transformation," Perry said. "That transformation was after watching the DVD `Gift of Life,' and I really started giving some, some thought about the issue of rape and incest, and some powerful stories in that DVD."
He cited Kissling during that meeting at an electric co-op.
"When the lady who was in it was looking me in the eye and saying, `You need to think this through,' she said, `I am the product of a rape' and she said `my life has worth,'" Perry said. "It was a powerful moment for me."
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The findings, published in Thursday's edition of the New England Journal of Medicine, come less than a week after the European Commission approved Avastin for treating women newly diagnosed with advanced ovarian cancer. The drug, known generically as bevacizumab, has not yet been approved by the Food and Drug Administration to treat ovarian cancer in the U.S.
Though Avastin has not been shown to prolong the lives of women with ovarian cancer and does come with significant side effects, it offers some hope for treating what remains the deadliest of gynecologic cancers, researchers said.
Ovarian cancer affects an estimated 200,000 women worldwide and causes 125,000 deaths each year, including more than 15,000 in the U.S. The cancer is particularly difficult to treat because it usually found after it has already spread to other organs. Surgery can remove only some of the tumors, and the two chemotherapy drugs most commonly used aren't very good at killing the cancer cells left behind.
But the study results suggest that treatment for ovarian cancer could improve for the first time in 15 years, said Dr. Robert Burger, a surgical oncologist at Fox Chase Cancer Center and lead author for one of the studies.
"I think we finally have a third component of treatment that works differently and that may greatly complement our therapeutics for ovarian cancers," he said.
Avastin is a biological antibody that interferes with a growth factor that cancer cells need to grow new blood vessels. When used in concert with chemotherapy, the drug helps keep cancers that have metastasized from growing and spreading. The FDA has approved the drug for use in a number of different cancers, including non-small-cell lung, kidney, brain and colon cancer.
Most recently, its use in treating breast cancer has become a source of controversy, as the FDA last month withdrew its approval of Avastin for patients with advanced breast cancer because the modest benefits were not seen as outweighing the drug's side effects. Physicians, however, can still prescribe Avastin off-label.
Burger's team, known as the Gynecologic Oncology Group, looked at what's called progression-free survival ? the length of time before the cancer gets worse ? in 1,873 women with newly diagnosed stage III and stage IV ovarian cancers, which typically have 5-year survival rates ranging from 18% to 45%. The investigators found that patients who received Avastin throughout their chemotherapy treatment experienced 14.1 months of progression-free survival, compared with the 10.3 months for patients who received standard chemotherapy plus a placebo. (Patients who received Avastin only during the initial treatments had 11.2 months of progression-free survival.)
The second study, by the International Collaboration on Ovarian Neoplasms, looked at 1,528 ovarian cancer patients and found a smaller difference in progression-free survival ? 24.1 months for those who took Avastin versus 22.4 months for those who didn't.
But when they focused on the 465 patients with the most advanced cancers, they found a bigger benefit ? 14.5 months with standard therapy alone and 18.1 months with Avastin added. They also found that overall survival for these patients was better with Avastin, at 28.8 versus 36.6 months.
On the whole, however, the researchers said they would not able to say much about overall survival rates until the patients had been tracked for a few more years.
The studies documented some notable side effects from the drug, including an increased risk of hypertension and gastrointestinal wall disruption, when a hole develops in the gastrointestinal tract. But these problems did not affect patients' quality of life, both studies found.
Avastin does not come cheap. The drug, made by Genentech Inc., can cost about $50,000 to $100,000 a year, which may be a lot to pay for just a few months more of remission, said Dr. Joanne Mortimer, director of the Women's Cancers Program at the City of Hope Comprehensive Cancer Center in Duarte. Many insurance companies cover at least some of that cost.
"Is it worth it?" said Mortimer, who served on two of three FDA advisory panels that debated the use of Avastin for breast cancer. "These are positive studies, but are they meaningful differences?"
Though the answer for breast cancer was no, the answer for ovarian cancer may be different, she said. Drugs for breast cancer are held to a higher standard because much more is known about how to treat the disease. The bar is lower for ovarian cancer because the treatment options aren't as good, Mortimer said.
Dr. Timothy Perren, a medical oncologist at Spire Leeds Hospital in Yorkshire, England, who led the second study, said the trials were promising steps that would "cement the place of Avastin in treating ovarian cancer." But researchers from both groups noted that more work needed to be done to figure out which patients would benefit the most from the drug and the best way to administer it.
The studies were funded by the National Institutes of Health, the National Institute for Health Research in Britain, Genentech and its parent company, Roche.
amina.khan@latimes.com
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Source: www.donanimhaber.com --- Wednesday, December 28, 2011
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Scientists at the NOAA Vents Program at Pacific Marine Environmental Laboratory and Oregon State University heard the March 11, 2011 Honshu, Japan earthquake using a hydrophone located near the Aleutian Islands of Alaska.
Credit: NOAA
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Source: http://wik.io/info/US/306933811
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BEIJING (Reuters) ? Police in China's restive far-western Xinjiang region killed seven "kidnappers in a hostage rescue", official media reported on Thursday, calling the suspects members of a "terror gang".
The kidnappers took two people hostage late on Wednesday in Pishan County in the southern part of Xinjiang, said the region's official news website (www.tianshannet.com).
When police responded "the assailants resisted arrest and launched assaults, killing one police officer and injuring another", said the report.
Seven of the suspects were shot dead and four were wounded and caught, said the report. The two abductees were freed.
The reports did not say explicitly whether the alleged kidnapping was related to ethnic tensions in the region, where many members of the largely Muslim Uighur minority resent the presence of Han Chinese and the controls of the central government.
"Pishan, an oasis county near the Taklamakan Desert, is located in the ethnic Uighur-dominated area of Xinjiang that is no stranger to violence," Xinhua news agency said in a report.
Calls to the Xinjiang government by Reuters were not answered.
In July 2009, Uighurs rioted against Han Chinese residents in Urumqi, the regional capital of Xinjiang, killing at least 197 people, mostly Han, according to official estimates.
Xinjiang sits astride south and central Asia, and China sees it as a bulwark in this volatile part of the world, making it all the more jumpy about unrest.
In September, courts in Xinjiang sentenced four people to death for violence in two cities over the summer that left 32 people dead.
The government blamed the incidents in Kashgar and Hotan -- both in the majority Uighur southern part of Xinjiang -- on religious extremists and separatists who want to establish an independent state called East Turkestan for their people who speak a Turkic language.
(Reporting by Chris Buckley; Editing by Ron Popeski)
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Sarah Tomlinson
Source: http://twitter.com/sarah_tomlinson/statuses/151295153729056768
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SHANGHAI (Reuters) ? China's central government will run a smaller fiscal deficit in 2012, according to a report by local media.
Fiscal outlays will increase 11 percent to 11.1 trillion yuan ($1.75 trillion) in 2012, against a revenue increase of 9 percent, according an unnamed finance ministry source cited by the Shanghai Securities Journal.
The figures, which emerged at the conclusion of the national Ministry of Finance Work Meeting on Monday, imply a 2012 fiscal deficit of 800 billion yuan, down 50 billion yuan from the expected 2011 deficit, the paper calculated.
A smaller deficit would disappoint those hoping for robust stimulus by the government to support growth. Industrial production slowed to its slowest pace in four years in November.
Concerns about slowing growth prompted policymakers to lower the required reserve ratio for banks on December 5, but analysts believe authorities have limited space for additional monetary stimulus, given the flood of bank lending that resulted from the previous round in 2008-10.
The relatively healthy state of China's public finances raised hopes that China would use fiscal spending to support the economy in 2012.
For 2011, China's full-year fiscal revenue is on pace to reach 10.2 trillion yuan, a 22 percent increase over 2010, the source said, while spending will reach 11 trillion yuan, an increase of 20 percent.
Of next year's 800 billion yuan deficit, the central government's share will be 550 billion yuan, a decrease of 150 billion yuan, while the local government share will be 250 billion yuan, an increase of 50 billion yuan.
Local government spending will be fueled by an increase in direct bond issuance by local governments, the source said. ($1 = 6.3364 yuan)
(Reporting by Gabriel Wildau; Editing by Jonathan Hopfner)
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Source: http://the-gadgeteer.com/2011/12/26/micro-gem-headphones-a-new-way-to-wear-pearls/
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ScienceDaily (Dec. 27, 2011) ? The 2007 Cosco Busan disaster, which spilled 54,000 gallons of oil into the San Francisco Bay, had an unexpectedly lethal impact on embryonic fish, devastating a commercially and ecologically important species for nearly two years, reports a new study by the University of California, Davis, and the National Oceanic and Atmospheric Administration.
The study, to be published the week of Dec. 26 in the early edition of the Proceedings of the National Academy of Sciences, suggests that even small oil spills can have a large impact on marine life, and that common chemical analyses of oil spills may be inadequate.
"Our research represents a change in the paradigm for oil spill research and detecting oil spill effects in an urbanized estuary," said Gary Cherr, director of the UC Davis Bodega Marine Laboratory and a study co-author.
On the foggy morning of Nov. 7, 2007, when the container ship collided with the San Francisco-Oakland Bay Bridge, bunker oil contaminated spawning habitats for the largest U.S. coastal population of Pacific herring -- a month before spawning season.
The new study, which analyzed Pacific herring embryos following the spill, highlights the effects of bunker oil on fish embryos in shallow water, the potential significance of sunlight interacting with oil compounds, and the extreme vulnerability of fish in early life stages to spilled oil.
Specifically, the study found that components of Cosco Busan bunker oil accumulated in naturally spawned herring embryos, then interacted with sunlight during low tides to kill the embryos. Laboratory-fertilized eggs, caged in deeper waters, were protected from the lethal combination of sunlight and oil, but still showed less severe abnormalities associated with oil exposure.
Crude oil is naturally occurring, liquid petroleum. Bunker oil is a thick fuel oil distilled from crude oil and burned on ships to fuel their engines. It is contaminated with various, sometimes unknown, substances.
The study builds on research following the 1989 Exxon Valdez spill, which released up to 32 million gallons of crude oil into the comparatively pristine environment of Prince William Sound, Alaska. That research established a new paradigm for understanding the effects of oil toxicity on fish at early life stages.
The new study suggests that this old paradigm is inadequate to explain the dramatic, lethal effects of very low levels of oil on fish embryos, even in an urban estuary with preexisting background pollution.
"Based on our previous understanding of the effects of oil on embryonic fish, we didn't think there was enough oil from the Cosco Busan spill to cause this much damage," Cherr said. "And we didn't expect that the ultraviolet light would dramatically increase toxicity in the actual environment, as we might observe in controlled laboratory experiments."
Researchers began the new study in February 2008. They analyzed the levels of oil-based compounds in caged herring embryos at four oiled and two non-oiled subtidal sites, all of which were at least 1 meter below the water's surface. Naturally spawned embryos from shallower sites were also analyzed.
Three months after the spill, caged embryos at oiled sites showed nonlethal heart defects typical of oil exposure.
But embryos from the shallower, intertidal zone not only exhibited the nonlethal heart defects, they also showed surprisingly high rates of dead tissue and mortality unrelated to heart defects.
"These embryos were literally falling apart with high rates of mortality," said Cherr.
In 2008, almost no live larvae hatched from the natural spawn collected from oiled sites.
The high death rates did not seem to be caused by natural or manmade causes unrelated to the spill, the researchers report. No toxicity was observed in embryos from unoiled sites, even those near major highways.
Embryos sampled two years later from oiled sites showed modest heart defects but no increased death rates.
Pacific herring is a commercially and ecologically important species. The fish travel in large schools, typically from the San Francisco Bay north to the Bering Sea, and serve as a forage fish for humpback whales, other mammals, birds and salmon. After two years at sea, they spawn in shallow areas of bays and estuaries.
"In San Francisco, herring is one of the last urban fisheries, and herring is an indicator for the health of the Bay," said Cherr.
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Source: http://www.sciencedaily.com/releases/2011/12/111227093057.htm
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TEHRAN (Reuters) ? An Iranian opposition leader who has been under house arrest since February has accused the Islamic establishment of intending to hold a "rubber-stamp" parliamentary election in March, his website Sahamnews reported on Monday.
Candidates began registering on Saturday for the March 2 vote, which will be the first litmus test of the clerical leadership's public standing since a disputed 2009 presidential vote that precipitated months of unrest.
Mehdi Karoubi was detained along with his wife, Fatemeh, when he urged supporters to gather for a Tehran rally in support of uprisings in the Arab world. His wife was later allowed out for medical treatment but he remains under house arrest.
"Officials do not believe in the people's vote and they are preparing themselves for a rubber-stamp election," his wife quoted him as saying during their weekly meeting, according to Sahamnews.
Candidate registration will last one week and then entrants will be screened for their political and Islamic qualifications by the hard-line Guardian Council electoral watchdog.
The Council has stopped hundreds of reformist candidates in the past from participating in elections. A grandson of late revolutionary leader Ayatollah Ruhollah Khomeini was banned from running for a 2008 parliamentary vote by the Council.
"The authorities want to repeat what they did in the 2009 presidential election by disqualifying the candidates.... and filling up the ballot boxes with counterfeit votes and creating an atmosphere of fear in the country," Karoubi's wife quoted him as saying, as reported by his website.
The 2009 election was followed by eight months of opposition protests that, while ultimately suppressed, pitched Iran into its deepest internal crisis since the Islamic Revolution and exposed divisions within the ruling elite.
The 73-year-old Karoubi and former prime minister Mirhossein Mousavi, who is also under house arrest with his wife, competed against President Mahmoud Ahmadinejad in the 2009 vote.
They became figureheads of the post-election protests by many who believed the vote was rigged to bring back President Mahmoud Ahmadinejad. Iranian authorities deny the charge and have portrayed the protests as a foreign-backed bid to undermine the Islamic government system.
Thousands of people, including senior reformers, were detained after the 2009 vote for fomenting unrest. Most of them have since been released, but more than 80 people have been jailed for up to 15 years and five have been sentenced to death.
Analysts say Ahmadinejad's allies want to secure a majority in the next parliamentary election to ease the way to winning the presidential vote in 2013.
Leading reformist politicians said pro-reform groups would not submit a separate list of candidates because the basic needs of a "free and fair" vote have not been fulfilled.
Authorities are concerned that a low turnout would question the establishment's legitimacy, and so hard-line conservative rulers have urged voters to participate in the March elections.
(Reporting by Mitra Amiri; Editing by Mark Heinrich)
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WTOP:
RICHMOND, Va. - Virginia motorists are being ticketed and convicted of a violation that is not a crime under state law: driving without proof of insurance.
Read the whole story: WTOP
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In America ?storm-chasers? are the intrepid types who pursue tornadoes, and sometimes hurricanes. But the Arctic Circle has its aurora chasers ? people who speed around in search of the best views of the aurora borealis, or Northern Lights.
?Last week we saw one that had everything ? spiralling, curtains, ribbons, greens and reds, and the whole sky lit up. We were amazed at what was unfolding before us,? says Andy Keen.
Five years ago he left his job running a charity in the UK to move to Ivalo, a remote village in northern Lapland, Finland, latitude 68 degrees ? two degrees above the Arctic Circle. ?I saw a TV documentary about the Northern Lights. So I went there to have a look. Now I?m absolutely addicted,? he says.
Mr Keen?s company, Aurorahunters, now takes seven tourists a week on hunting trips in the Arctic wilderness to search for the Northern Lights?There are similar companies operating elsewhere in Finland and in neighbouring Norway where the official tourism website describes the aurora as ?a tricky lady?. It adds: ?You never know when she bothers to turn up. This diva keeps you waiting??
When a location has been selected, Mr Keen and his group jump into minibuses and head into the wilderness, sometimes taking to sledges pulled by huskies to reach the most remote areas. They often see moose and bear tracks and have ventured as far north as the Arctic Ocean.
All to get the best vantage point to see the aurora borealis, named after the Roman goddess of dawn (Aurora) and the Greek name for the north wind (Boreas)?
RTFA. Details about the causes, predictions. Suggestions about chasing and photographing the elusive beauty of the aurora. All useful.
Be the first to like this post.
Source: http://eideard.com/2011/12/26/tornado-alley-for-electrons-chasing-the-aurora-borealis/
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Paul Thurrott
Source: http://twitter.com/thurrott/statuses/150580707691986944
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A Visionary Tale I have spent my whole lifestyle mastering what it is to get human and I typically affiliated intently with Tv characters including Star Trek's Vulcan, Mr. Spock and android Commander Info. This post is just one particular simplified component of what it can be for being human; or rather I should qualify that as stating a concentrated and purposeful human.I canada goose jacket am dyslexic and my most important problem is in auditory comprehension. I typically need to 'see' one thing as a way to 'get' it. As a result, I have designed a eager perception for dynamics, designs and tendencies over time. I also advocate very simple language to make sure that we are able to all know and develop, easily. And all of this need to even be enjoyment!Immediately, after just returning from a coaching functionality, I'm pumped (over again) and stimulated with notions that I can only liken to an ocean inflammation and falling. Coaching guru Anthony Robbins as soon as explained he is read through about 700 publications; I'm steadily attaining on him! Over the years I have digested every little thing I have go through, and keep on to produce on what it's to get human. Like a result, my mind normally displays me a facet that I need to encase and showcase. This really is a single these kinds of facet.I've place collectively a seminar termed the Pyramid of Lifestyle that highlights where we're within our social evolution and makes an attempt to convey ideas on how we operate, cope and increase on managing the globe around us and within us. What I would like to offer here's the fundamental composition that I take advantage of.Taking a pyramid and dividing it horizontally twice, now we have 3 sections. I take advantage of every single portion to illustrate a facet of our human-ness. The tiny best triangle I exploit to indicate our Visionary or Dreamer. The middle portion would then be our Organizer or Coordinator. The foundation segment would then be our Worker or Technician. You might also use extra abstract terms which include Seer, Gatherer and Creator. I attempted to get exciting with this and generate an acronym that might stick. I settled with Visionary, Organizer and Worker to make 'VOW'. I VOW to stick to this idea...hmm.Obtaining proven you the structure, what do they represent? It is wherever it gets appealing, as I have to focus on presenting the knowledge and canada goose parka hold regulate to the effect of what each segment has on us. I say this because my ideas often consider the product and extrapolate to 'what if' and I need to keep this informative article to all around 1500 phrases.Our Visionary would be the half of us that gives us goose bumps! It really is those strategies that pop into our head that will, if adopted by, deliver some amazing enhancement for us. They nearly always get dismissed when we 'see sense' and see just the amount we might really have to make investments (with time energy and perhaps capital) to produce it true. Or perhaps we just do not commit the time to discover what's concerned as we have been usually 'just to busy'. What I come to feel most of us eliminate is usually a bit of our self Canada Goose Kensington Parka after we allow goals go. Just how wonderful would ALL our lives be if we did realize a number of our dreams? Consider acquiring all you want, no shortages of anything at all, yet preserving a small impression on our surroundings. A dream you say? Try visualizing it and as soon as you'll be able to see that image in your head, go deeper and see what you'd be carrying out minute by moment in a typical day. Then see how we'd be able to build each of all those things that assist you in that dream. Now step again and question the question, "What could it be that stops me from executing individuals things?" That is after you get to determine exactly where we are verses where by we can be. Our Visionary within us dismisses goals and wishes a lot with the time.The 'why' will come from what every single of us believes. It's about our possess limits, our self-talk. We'd like to get started on respecting and embracing this closed out Visionary element of our self. We need to get tranquil and hear it. We want to close our eyes and see what it shows us. We want to feel on top of things sensation what's doable. For those who can do that, start off composing down what you find out. Now publish it! Yes, you heard me, publish it. Put it out there. I am doing it, so are you able to! The intent here is to advertise accountability. Should you offer you up a thing, you will obtain a reaction sure, but a lot more importantly, you hold all by yourself accountable with the eyes of some others and that is a powerful motivator. Some feedback might be from dissenters, but most suggestions will likely be supportive. Numerous of us by now understand how daily life should be run, but get slapped upside the head each day with 'reality'. (As an example, many of us are just two or three spend cheques absent from missing those people relentless bills). I am advocating creating your own personal fact given that it really is probably considerably similar to most everyone else. Each individual of us also dismisses our dream as fanciful, or unattainable with no stopping to believe some others could be contemplating a great deal exactly the same.The Organizer could be the aspect of us who enjoys to put our vision into motion to check out if it is workable. The Organizer sets out what on earth is necessary with regard to support, components, monies, effort and time. Put simply, our Organizer turns the vision into a working plan. Yet again every one of us know how to do this. The number of moments have you ever gone out to choose up a newspaper or maybe a chocolate bar? To begin with, you will get the concept (Eyesight), then you set out how you'd visit it (Organize); which might be to seize some cash, keys, place on your own coat and footwear and stroll toward the local ease retailer. We're all qualified at arranging and however some of us appear to run our lives in an untidy method. The reason as I see it truly is Canada Goose Kensington once again that we absence concentration. I'm a great organizer when i am in my groove. It is when I am not following my desires that I become imprecise, listless, and that turns into a type of 'why really should I care' mild depressed feeling which manifests as disorganized behaviour. In other words, when my Visionary is offline, it impacts other parts of me, specially, my Organizer. So I have to preserve my visions up front so I can always concentrate on them. Lots of people place up Dream boards, or Treasure Maps around the home, that exhibit what they would like to reach in life. It retains it firmly in concentrate for them. There is certainly approach in this particular obvious madness! It has a trickle-down impact.When these ideas get translated into steps you've engaged our final participant, the Worker. This participant is without doubt one of the most highly effective parts. As soon as our plan is affreux out, our Employee goes to work. The following I digress to be able to make clear why men typically do mindless simple jobs. In case you question us guys, why we're correcting up some torn page inside of a e-book, or repairing some ripped three-ring binder sheets with stick-on ringlets, we might generally not have a distinct reaction. I sat and nevertheless about this a while as my attractive wife has introduced it up on numerous occasions. It lastly dawned on me that I used to be participating my technician, my employee like a means to get a fix, a sensation of fulfillment of completion.The idea of laying a 3000 brick walkway all-around my residence (which happens to be one of my biggie tasks) is a eyesight my technician enjoys and nevertheless it can be overpowering because it needs tons of preparing and of course loads of money, time and effort. It's not a thing my Organizer could get a deal with on and method for since some areas can't be set down. I really feel incomplete. My mindless, irrelevant, low priority 'what in the world are you currently executing that for?' endeavor assists me experience beneficial. I won't be able to converse for ladies, as it's not in my context (at this time). So remember to females, be form to us guys after you really feel we are just kicking tyres. We are most likely having complications environment out a approach for a even larger activity. Just consult us what is on our mind. Chances are you'll be astonished!Hopefully, you can get one thing out of my Personalized Pyramid. There's quite a bit a lot more involved about the principle than I will cover right here. It goose jakke truly is affreux out to obtain you pondering (together with your Visionary not surprisingly) also to illustrate how often we dismiss our aims or goals in favour of remaining with the rut we've accepted as our daily everyday life. I say dare to dream. I say request assistance for ones dream and be prepared to assistance some others exactly the same way. It may be less complicated than you now think.I use the following illustration to aid visualize the power on the lots of, verses the one particular. I have a 300lb concrete paving stone delivered which must be positioned as my entrance door stage. It is way too large for me to carry. I commit some days figuring out a prepare, building a jig or crane and relocating it into position. My contemplating relies on engaging in it alone, without having assist. Even so, I could 'put it out there'. Then potentially a neighbour would arrive through and assist out. Together we could elevate the whole issue into area and also have it performed in a very few minutes. Also, the possibilities is that we could do the exact same endeavor 20 or thirty moments much more inside the time it would just take me by yourself to maneuver just my slab! Talk about the sum of your parts being better compared to the complete! All it will take is requesting what I want.Visualize it and place it out there. Your dream has far more possibility of turning out to be a reality if more individuals know about it and so are offered the opportunity to help it.
Source: http://bbhofmath.ning.com/xn/detail/2056690%3ABlogPost%3A307382
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Army Pfc. Bradley Manning, right, is escorted into a courthouse in Fort Meade, Md., Saturday, Dec. 17, 2011, for a military hearing that will determine if he should face court-martial for his alleged role in the WikiLeaks classified leaks case. Manning is suspected of being the source in one of the largest unauthorized disclosures of classified information in U.S. history. (AP Photo/Patrick Semansky)
Army Pfc. Bradley Manning, right, is escorted into a courthouse in Fort Meade, Md., Saturday, Dec. 17, 2011, for a military hearing that will determine if he should face court-martial for his alleged role in the WikiLeaks classified leaks case. Manning is suspected of being the source in one of the largest unauthorized disclosures of classified information in U.S. history. (AP Photo/Patrick Semansky)
Army Pfc. Bradley Manning, right, is escorted into a courthouse in Fort Meade, Md., Saturday, Dec. 17, 2011, for a military hearing that will determine if he should face court-martial for his alleged role in the WikiLeaks classified leaks case. Manning is suspected of being the source in one of the largest unauthorized disclosures of classified information in U.S. history. (AP Photo/Patrick Semansky)
Army Pfc. Bradley Manning, at center wearing glasses, is escorted into a courthouse in Fort Meade, Md., Saturday, Dec. 17, 2011, for a military hearing that will determine if he should face court-martial for his alleged role in the WikiLeaks classified leaks case. Manning is suspected of being the source in one of the largest unauthorized disclosures of classified information in U.S. history. (AP Photo/Patrick Semansky)
David Coombs, attorney for Army Pfc. Bradley Manning, walks towards the courthouse entrance at Fort Meade, Md., Saturday, Dec. 17, 2011, during a recess in a military hearing that will determine if Army Pfc. Bradley Manning should face court-martial for his alleged role in the WikiLeaks classified leaks case. Manning is suspected of being the source in one of the largest unauthorized disclosures of classified information in U.S. history. (AP Photo/Patrick Semansky)
Lt. Dan Choi, gay veteran and activist, center left, and retired US Army Colonel and diplomat Ann Wright, right, march with others in support of Army Pfc. Bradley Manning, present on base at a military court hearing, at Ft. Meade, Md., Saturday, Dec. 17, 2011. Prosecutors began presenting their case that Manning was the source of the WikiLeaks website's collection of U.S. military and diplomatic secrets. ( AP Photo/Jose Luis Magana)
FORT MEADE, Md. (AP) ? The young Army intelligence specialist accused of passing government secrets spent his 24th birthday in court Saturday as his lawyers argued his status as a gay soldier before the repeal of "don't ask, don't tell" played an important role in his actions.
Lawyers for Pfc. Bradley Manning began laying out a defense to show that his struggles as a gay soldier in an environment hostile to homosexuality contributed to mental and emotional problems that should have barred him from having access to sensitive material.
Manning is accused of leaking hundreds of thousands of sensitive items to the anti-secrecy group WikiLeaks, including Iraq and Afghanistan war logs, State Department cables and a military video of a 2007 American helicopter attack in Iraq that killed 11 men, including a Reuters news photographer and his driver.
The Obama administration says the released information has threatened valuable military and diplomatic sources and strained America's relations with other governments. Manning's lawyers counter that much of the information that was classified by the Pentagon posed no risk.
The military is conducting a hearing in a small courtroom on an Army post outside Washington to determine whether prosecutors have enough evidence to bring Manning to trial, where he could face a term of life in prison as a traitor.
Prosecutors began presenting evidence to substantiate the charges against Manning.
Army criminal investigators described evidence they collected that links Manning to the WikiLeaks website's collection of U.S. military and diplomatic secrets.
But among the first issues to arise Saturday was whether Manning's sexual orientation is relevant to the case against him.
The basis for the charges Manning faces are transcripts of online chats with a confidant-turned-government-informant in which Manning allegedly confesses his ties to WikiLeaks and also reveals he is gay.
Maj. Matthew Kemkes, a defense lawyer, asked Special Agent Toni Graham, an Army criminal investigator, whether she had talked to people who believed Manning was gay or found evidence among his belongings relating to gender-identity disorder. The condition often is described as a mental diagnosis in which people believe they were born the wrong sex.
Graham said such questions were irrelevant to the investigation. "We already knew before we arrived that Pfc. Manning was a homosexual," Graham said.
Prosecutors objected several times to the questions. Kemkes responded that if the government can argue that Manning intended to leak secrets, "what is going on in my client's mind is very important."
During its cross examination of Graham, Manning's defense team also sought to convince the court that not all of the material he is accused of leaking is classified.
Graham, who collected evidence from Manning's living quarters and workplace, testified that among the items seized was a DVD marked "secret" that contained a military video showing the 2007 incident in which Apache attack helicopters gunned down unarmed men in Iraq.
The video was taken from the cockpit of one the helicopters. WikiLeaks posted the video in April 2010, sparking questions about the military's rules of engagement and whether more needed to be done to prevent civilian casualties. The gunners can be heard laughing and referring to the men as "dead bastards."
Kemkes, one of Manning's lawyers, asked Graham whether she knew the video was unclassified. She said she didn't. "In fact, it was an unclassified video," Kemkes said.
At the time the video was posted by WikiLeaks, the Pentagon called it a breach of national security and it was believed to be secret.
Although WikiLeaks had been posting sensitive information to the Web since 2006, release of the Apache video drew worldwide attention to the organization as it prepared to publish secret documents on the war in Afghanistan.
Manning's appearances Friday and Saturday in the Fort Meade courtroom mark the first time he has been seen in public after 19 months in detention. The Oklahoma native comes to court in Army camouflage fatigues and wearing dark-rimmed glasses. Slight and serious, he takes notes during the proceedings.
An Army appeals court on Friday rejected a defense effort to have the presiding officer, Lt. Col. Paul Almanza, because of alleged bias. Separately, lawyers for WikiLeaks and founder Julian Assange are asking the military's highest appeals court to guarantee two seats in the Fort Meade courtroom.
Manning's hearing is open to the public, with limited seating. Inside the courtroom, no civilian recording equipment is allowed. Instead of a judge, a presiding officer delivers a recommendation as to whether prosecutors have enough evidence to bring a suspect to trial. A military commander then makes the final decision.
The case has spawned an international support network of people who believe the U.S. government has gone too far in seeking to punish Manning.
More than 100 people gathered outside Fort Meade for a march in support of Manning, some holding signs declaring "Americans have the right to know. Free Bradley Manning" and "Blowing the whistle on war crimes is not a crime."
Todd Anderson, 64, said he drove from New York City to take part. "I think this man showed a great deal of courage, the kind of thing I wouldn't have the courage to do, and I really consider him to be a hero," Anderson said.
Juline Jordan, 46, said she flew in from Detroit just for the day. "I support what he did because he exposed some horrific war crimes and horrific things done at the hands of the United States government and the Department of Defense, and he's a hero for that," Jordan said.
In London, several dozen protesters from gay organizations, the Occupy London protest camp and other groups rallied outside the U.S. Embassy Saturday calling for Manning's release and offering birthday wishes.
___
Associated Press writers Jill Lawless in London, Richard Lardner and Mark Sherman in Washington and Brian Witte at Fort Meade contributed to this report.
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All of the data in the world?and the amount is growing at a frightening rate?won?t help researchers solve the big problems if they can?t make sense of it. Which is why a team of researchers from Harvard University and the Broad Institute of Harvard and M.I.T. has developed analytical data-mining software that can find an oasis of meaning in a desert of numbers. They?ve used the software to find insights on the socioeconomic impact of obesity, bacteria in the gut and baseball.
The software teases out relationships among data points (potentially millions of them) and measures the strength of these connections. As the researchers report in a paper appearing in the December 16 issue of the journal Science, most data-mining tools used today can either find correlations between data or determine how solid those connections are?few can do both.
?When we started this project we wanted a way to summarize what was in these datasets in a very simple way, asking what were the variables in these datasets that are most strongly associated,? says David Reshef, a co-first author of the paper and graduate student in the Harvard-M.I.T. Health Sciences and Technology program. ?It?s a very simple question but it turned out to be very complicated because variables can be related in lots of different ways and there are various methods for finding different patterns.?
David Reshef?working with younger brother Yakir Reshef, Broad Institute associate member Pardis Sabeti and Harvard computer science professor Michael Mitzenmacher?tested the tool on social, economic, health and political data from the World Health Organization (WHO) and its partners. The data pool was large, covering 200 countries and containing 357 data variables per country, including household income and obesity.
The tool is part of a larger program the researchers call MINE (Maximal Information-based Nonparametric Exploration). It examined every possible combination of variables (more than 60,000 of them) and a list of relationships ranked by the strength of one variable?s statistical dependence on the other (i.e. how much one variable is related to the other).
One identified relationship, for example, was between household income and female obesity. From this pairing, the researchers saw that the data from many countries follow a parabolic curve, with obesity rates rising with income but peaking and tapering off after income reaches a certain level. However, in the Pacific Islands, where female obesity is a sign of status, the rate of obesity followed a completely separate trend from the rest of the countries in the world, climbing rapidly even at low incomes.
The idea is to use MINE to generate new ideas and connections that no one has thought to look for before, says Yakir Reshef, a co-first author of the paper and a Fulbright scholar at the Weizmann Institute of Science in Israel. ?The interdisciplinary nature of the project shows to us the widespread application of this work,? he adds. ?It doesn?t matter whether it?s global health data, genomic data or Internet search statistics?on some level it?s all the same.? The researchers explain their work in more detail on their Web site and in a video accompanying their paper.
In another test, they took nearly 6,700 pieces of data related to microorganisms that live in the gut collected by Harvard colleague Peter Turnbaugh. The software made more than 22 million comparisons and narrowed in on a few hundred patterns of interest that had not been observed before.
The researchers also tested the software on baseball. They found that the statistics that most related to a player?s salary were hits, total bases and an aggregate statistic that reflects how many runs a player generates for a team. During the 2008 season the Tampa Bay Devil Rays, Atlanta Braves and current world-champion Saint Louis Cardinals (not surprisingly) proved to have the fewest number of overpaid players compared to the number of ?overperforming? players on their rosters. Predictably, the New York Yankees finished dead last. It?s not easy to find overperforming players when your payroll is the highest in baseball.
Photo: Brothers David Reshef (second from left) and Yakir Reshef (right) developed MIC under the guidance of advisers Michael Mitzenmacher (left) of the Harvard University School of Engineering and Applied Sciences and Pardis Sabeti (second from right) of the Broad Institute. Image courtesy of ChieYu Lin
Source: http://rss.sciam.com/click.phdo?i=cd3e02f9c8205fa7cce86861821720fc
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New York ? Noah and Allie's dramatic kiss in the rain will now be adapted for the stage and set to a rousing score, as will Austin Powers and... Rocky?
There's no shortage of musicals based on films currently playing on Broadway ? Sister Act, Mary Poppins, The Lion King, Priscilla Queen of the Desert, and, most famously, Spider Man: Turn Off the Dark. More are due in 2012, including Ghost and Newsies. It's no surprise, then, that producers are mining the world of cinema for yet more possibilities. But not every project being developed seems like a natural choice. Here's a look at six recently announced movie-inspired musicals that, on the surface, seem like odd fits for the rialto:??
The Notebook
The Notebook quickly achieved classic tearjerker status with its time-jumping narrative of a tortured romance between two passionate lovers. A musical version of the Ryan Gosling-Rachel McAdams film (which is itself based on a Nicholas Sparks book) has been in the works since 2009 ? written by One Tree Hill star Bethany Joy Galeotti, of all people. In an interview this week with CBS' The Early Show, Sparks revealed that the project is now moving forward, with eyes set on the Great White Way. Perfect, says Jen Carlson at Gothamist, another medium in which girls can torture their boyfriends with Notebook viewings. After all, says Jean Bentley at Zap2it, "if you're a lady, you're genetically predisposed to love the crap outta this."
Austin Powers
None other than the International Man of Mystery himself, Mike Myers, is working on adapting the Austin Powers films into a Broadway musical (though reports are that he won't star in it). Casey Nicholaw, the co-director of the stage smash The Book of Mormon, is in talks to direct. Jamie Feldmar at Gothamist isn't optimistic: The only people who benefit from this deal are "Myers, for whom this will be a total cash cow, and the legions of Midwestern tourists who will feed him."
Rocky
No one watching Rocky Balboa for the first time 35 years ago was thinking "I can't wait for this musical!" says Julie Miller at Movieline. Nevertheless, a song-and-dance version of the venerable underdog boxing film is being vigorously prepped, with music to be written by esteemed Broadway music team Lynn Ahrens and Stephen Flaherty. Actually, says Mandi Bierly at Entertainment Weekly, this is not "as crazy as it sounds." Remember, Rocky, like the best Broadway musicals, is at heart a love story.
Because of Winn-Dixie
The Notebook isn't the only tearjerking novel-turned-film poised to morph into a musical. Because of Winn-Dixie, the 2000 novel about a stray dog who helps a young girl rekindle a relationship with her father ? the source material for a 2005 movie starring AnnaSophia Robb and Dave Matthews ? is also being adapted. Duncan Sheik, the soft rocker-turned Tony-winning composer (Spring Awakening) will write the music, while plans call for a real dog to star. "Yes, a musical starring a dog in the lead role," says The Broadway Blog. Though, given the talent involved with the score, this production may be "nothing to sniff at."
Tuck Everlasting
Director Casey Nicholaw is apparently very keen on film-to-musical adaptations. In addition to his involvement with the Austin Powers musical, Nicholaw will reportedly direct a musical version of the 1975 children's novel Tuck Everlasting (which was turned into a film twice, in 1985 and 2002, starring Alexis Bledel, Jonathan Jackson, and Sissy Spacek). The story follows a girl's friendship with a boy whose family becomes immortal after drinking out of an enchanted fountain in the forest.
Romy and Michele's High School Reunion
A musical version of the '90s comedy Romy and Michelle's High School Reunion ? which starred Lisa Kudrow and Mira Sorvino as flighty, unaccomplished twentysomethings who attend their small town high school's reunion ? received a private industry reading this week. Producers of the show revealed that a Broadway perch is the ultimate goal. If nothing else, says Mallika Rao at The Huffington Post, the film's classic "Time After Time" dance scene must be included.
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